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What is Sickle cell Disease

A sickle cell is an inherited blood disorder that affects red blood cell.
People with this have red blood cells with a lot of hemoglobin.
These people sometimes have there red blood cells turn in to a sickle shape.
The people with this disease have there blood vessels blocked off.
Another name for sickle cel is drepanocytosis.
Sickle cell decreases the cells flexibility and results in a risk of various complications.
Sickle cell occurs because of a mutation in the haemoglobin gene.
People get sickle cell in childhood were malaria is more common.
People with one of the two sickle cell disease are more resistant to malaria.
The disease in the united states is approximately 1 in 5,000.

The sign and symptoms of sickle cell

Some of the sign are shortness of breath, dizziness, headache, coldness in hands and feet, pale skin, chest pain.
There is also an infection that can damage the spleen.
Here is some thing that is connected to sickle cell and that name is acute chest.
Children who has sickle cell grows slowly than other children. William_Cordozo_Sickle_Cell.jpg
There is two different strokes that can occur.
One is when blood vessel are blocked from the brain.
Another way is a blood vessel in your brain will burst.
Can cause eye problem to people with sickle cell.
People with sickle cell disease will have a painful and unwanted erection.
Another symptom is ulcers on the leg.
People can have multiple organ failure.

The inheritance pattern,treatment and incidence

The pattern is usually odd.
Usually both parents have to have symptom free genetic carriers.
The pattern inheritance of sickle cell is recessive.
The way to cure sickle cell is a bone marrow transplant.
It affects 72000 people or 1 in every 1000 to 14000 hispanic. It also affects about 2 million americans.

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Reference

http://www.sicklecelldisease.org/about_scd/index.phtml http://www.nhlbi.nih.gov/health/dci/Diseases/Sca/SCA_SignsAndSymptoms.html http://www.wrongdiagnosis.com/s/sickle_cell_anemia/inherit.htm

Sickle cell questions

What is the definition of sickle cell?


What does sickle cell decrease?




What is the pattern normal or rare, and how many americans does it affect?